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Nontypeable Haemophilus influenzae patho-adaptation within the aireways of chronic obstructive pulmoray disease patients with long-term microbial persistence

AuthorsMoleres, Javier ; Mell, Joshua Chang; Ehrlich, Rachel L.; Fernández-Calvet, Ariadna ; Marti, Sara; Cuesta, Sergio; Caballero, Lucía ; Euba, Begoña ; Rodríguez-Arce, Irene ; Ehrlich, Garth D.; Liñares, Josefina; Garmendia, Juncal
Issue Date21-Sep-2017
Citation7th European Conference on Prokaryotic and Fungal Genomics ProkaGENOMICS (2017)
AbstractIntroduction. The respiratory pathogen nontypeable Haemophilus influenzae (NTHi) persistently infects a significant proportion of Chronic Obstructive Pulmonary Disease (COPD) patients’ lower airways, and is usually associated with acute exacerbations of this chronic disease. Objectives. Based on the hypothesis that the COPD may be a unique niche favouring NTHi adaptation, this work aimed to unravel NTHi evolutionary dynamics in the COPD lungs over time, with the goal of identifying genomic patho-adaptive features.
DescriptionTrabajo presentado en el 7th European Conference on Prokaryotic and Fungal Genomics (ProkaGENOMICS), celebrado en Gottingen (Alemania), del 19 al 22 de septiembre de 2017)
Appears in Collections:(IDAB) Comunicaciones congresos
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