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One more step against nanotoxicity: Hierarchical particles designed to antifungal properties

AuthorsLucas-Gil, Eva de; Fernández Lozano, José Francisco ; Rubio Marcos, Fernando
KeywordsAntifungal activity
Safe hierarchical structure
Abrasion interactions
Issue Date2017
CitationMaterials and Design 134: 188- 195 (2017)
AbstractThe interest that awakens the ZnO as material is greatly extended both by its unique properties as by its wide variety of applications. Within these applications, antimicrobial activity is gaining relevance. Especially, the bactericidal activity of ZnO nanoparticles is outstanding but little is known about antifungal activity. In addition, the recent discussion about the potential toxicity of nanoparticles and their massive use places them in the spotlight. In response to this emerging problem, a simple and general approach to synthesize hierarchical structure of ZnO is reported. A formation mechanism of these surprising structures is proposed. Moreover, the obtained zinc oxide hierarchical particles improves the antifungal activity towards Aspergillus niger in contrast to ZnO micro or nanoparticles. Due to surprising results, the different action mechanisms of ZnO hierarchical particles against fungi are studied. Thus, we pose a novel physical mechanism by which ZnO hierarchical particles achieve excellent fungicidal results.
Publisher version (URL)http://dx.doi.org/10.1016/j.matdes.2017.08.038
Identifiersdoi: 10.1016/j.matdes.2017.08.038
e-issn: 0264-1275
Appears in Collections:(ICV) Artículos
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