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http://hdl.handle.net/10261/188937
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Xavier, Ana A. O. | - |
dc.contributor.author | Garrido-López, Juan E. | - |
dc.contributor.author | Aguayo-Maldonado, Josefa | - |
dc.contributor.author | Garrido Fernández, J. | - |
dc.contributor.author | Fontecha, F. Javier | - |
dc.contributor.author | Pérez Gálvez, Antonio | - |
dc.date.accessioned | 2019-08-23T07:03:37Z | - |
dc.date.available | 2019-08-23T07:03:37Z | - |
dc.date.issued | 2019-08-07 | - |
dc.identifier.citation | Antioxidants 8(8): 291 (2019) | - |
dc.identifier.uri | http://hdl.handle.net/10261/188937 | - |
dc.description.abstract | Human milk is a complex fluid with nutritive and non-nutritive functions specifically structured to cover the needs of the newborn. The present study started with the study of carotenoid composition during progress of lactation (colostrum, collected at 3–5 d postpartum; mature milk, collected at 30 d postpartum) with samples donated from full-term lactating mothers (women with no chronic diseases, nonsmokers on a regular diet without supplements, n = 30). Subsequently, we applied an in vitro protocol to determine the micellarization efficiency of the carotenoids, which were separated by HPLC and quantified by the external standard method. That in vitro protocol is tailored for the biochemistry of the digestive tract of a newborn. To the best of our knowledge, the present study is the first report of carotenoids micellar contents, obtained in vitro. This study reveals, from the in vitro perspective, that colostrum and mature milk produce significant micellar contents of carotenoids despite lipids in milk are within highly complex structures. Indeed, the lactation period develops some influence on the micellarization efficiency, influence that might be attributed to the dynamics of the milk fat globule membrane (MFGM) during the progress of lactation. | - |
dc.description.sponsorship | This research was funded by the Ministerio de Ciencia, Investigación y Universidades, Agencia Estatal de Investigación, grant number AGL2017-87884-R. A.A.O.X. is a fellow of the Science without Borders Program of the Brazilian National Council for Scientific and Technological Development, fellowship 238163/2012-1. | - |
dc.language.iso | en | - |
dc.publisher | Multidisciplinary Digital Publishing Institute | - |
dc.relation | info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/AGL2017-87884-R | - |
dc.relation | AGL2017-87884-R/AEI/10.13039/501100011033 | - |
dc.relation.isversionof | Publisher's version | - |
dc.rights | openAccess | - |
dc.subject | Breastfeeding | - |
dc.subject | Newborn | - |
dc.subject | Human colostrum | - |
dc.subject | Carotenes and xanthophylls | - |
dc.subject | In vitro digestibility | - |
dc.subject | Micellar lipids | - |
dc.title | In vitro digestion of human milk: influence of the lactation stage on the micellar carotenoids content | - |
dc.type | artículo | - |
dc.identifier.doi | 10.3390/antiox8080291 | - |
dc.description.peerreviewed | Peer reviewed | - |
dc.relation.publisherversion | https://doi.org/10.3390/antiox8080291 | - |
dc.identifier.e-issn | 2076-3921 | - |
dc.date.updated | 2019-08-23T07:03:37Z | - |
dc.rights.license | http://creativecommons.org/licenses/by/4.0/ | - |
dc.contributor.funder | Agencia Estatal de Investigación (España) | - |
dc.contributor.funder | Ministerio de Ciencia, Innovación y Universidades (España) | - |
dc.contributor.funder | Conselho Nacional de Desenvolvimento Científico e Tecnológico (Brasil) | - |
dc.relation.csic | Sí | - |
dc.identifier.funder | http://dx.doi.org/10.13039/501100011033 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003593 | es_ES |
dc.identifier.pmid | 31394852 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | With Fulltext | - |
item.languageiso639-1 | en | - |
Aparece en las colecciones: | (IG) Artículos (CIAL) Artículos |
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in_vitro_digestion_of_human_milk.pdf | 1,14 MB | Adobe PDF | Visualizar/Abrir |
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