English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/18814
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Título

Adsorption of recombinant human bone morphogenetic protein rhBMP-2m onto hydroxyapatite.

AutorBoix, T.; Gómez-Morales, J.; Torrent-Burgués, J.; Monfort, A.; Puigdomènech, Pere
Palabras claveRhBMP-2m
Hydroxyapatite
Adsorption
Langmuir isotherm
Fecha de publicaciónmay-2005
EditorElsevier
CitaciónJournal of Inorganic Biochemistry 99(5): 1043-1050 (2005)
ResumenRecombinant human mature bone morphogenetic protein 2 (rhBMP-2m) has been expressed to study its adsorption onto precipitated hydroxyapatite (HA). The influence on the adsorption process of different parameters such as pH and concentrations of calcium, phosphate or NaCl has been investigated. Although the adsorption proceeds rapidly at the initial stages, the maximum adsorbed amount is reached after four hours. The process is notably influenced by adding calcium or phosphate to the system but, while calcium ions increase the adsorption of rhBMP-2m onto HA, phosphate ions inhibit it. The influence of pH and NaCl concentration are notable but less important than those of calcium and phosphate. The adsorption data fit well to a Langmuir adsorption isotherm. The values of the isotherm parameters have been calculated and discussed, and an adsorption mechanism has been proposed.
Descripción8 figures, 2 tables.
Versión del editorhttp://dx.doi.org/10.1016/j.jinorgbio.2005.01.011
URIhttp://hdl.handle.net/10261/18814
DOIdoi:10.1016/j.jinorgbio.2005.01.011
Aparece en las colecciones: (IACT) Artículos
Ficheros en este ítem:
No hay ficheros asociados a este ítem.
Mostrar el registro completo
 


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.