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Título

A synthetic alternative to natural lecithins with antimicrobial properties

AutorPérez, Lourdes; Infante, María Rosa; Pons Pons, Ramón; Morán, María del Carmen; Vinardell, M. Pilar; Mitjans, Montserrat; Pinazo Gassol, Aurora
Palabras claveAmmino acid arginine
Biocompatible multifunctional surfactants
Fecha de publicación14-may-2004
EditorElsevier
CitaciónColloids and Surfaces B Biointerfaces 35(3-4): 235-242 (2004)
ResumenTwo soft biocompatible cationic surfactants from the amino acid arginine, 1,2-dilauroyl-3-acetylarginyl-rac-glycerol (1212RAc) and 1,2-dimirystoyl-3-acetylarginyl-rac-glycerol (1414RAc), were prepared. Their physicochemical properties show that they can be classified as multifunctional surfactants with self-aggregation behaviour comparable to that of short-chain lecithins. The two surfactants can simultaneously stabilise water-in-oil (W/O) droplets and oil-in-water (O/W) droplets, forming multiple emulsions. They have antimicrobial activity similar to that of conventional cationic surfactants and are as harmless as amphoteric betaines. These surfactants constitute an interesting alternative to the diglycerides and lecithins in formulations that require antimicrobial properties.
Descripción8 pages, 4 figures, 5 tables.-- PMID: 15261036 [PubMed].-- Printed version published Jun 1, 2004.
Versión del editorhttp://dx.doi.org/10.1016/j.colsurfb.2004.03.014
URIhttp://hdl.handle.net/10261/18540
DOI10.1016/j.colsurfb.2004.03.014
ISSN0927-7765 (Print)
1873-4367 (Online)
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