Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/185262
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Marqueño, Anna | es_ES |
dc.contributor.author | Blanco, Maria | es_ES |
dc.contributor.author | Maceda-Veiga, Alberto | es_ES |
dc.contributor.author | Porte Visa, Cinta | es_ES |
dc.date.accessioned | 2019-07-02T09:13:57Z | - |
dc.date.available | 2019-07-02T09:13:57Z | - |
dc.date.issued | 2019-06-17 | - |
dc.identifier.citation | Environmental Science and Technology (2019) | es_ES |
dc.identifier.uri | http://hdl.handle.net/10261/185262 | - |
dc.description.abstract | This work applies ultrahigh performance liquid chromatography coupled with high-resolution mass spectrometry (UPLC-HRMS) to characterize for the first time the lipidome of the skeletal muscle of two fish species (Barbus meridionalis, Squalius laietanus) collected in a Mediterranean River affected by urban and industrial outflows. The untargeted analysis allowed a clear separation of the lipidome of fish from polluted and reference sites; phosphatidylcholines (PCs), phosphatidylethanolamines (PEs), and their lyso and ether-linked forms were among the distinctive features. The targeted analysis consistently detected a decrease in PC-plasmalogens (36:4, 36:6, 38:6) and highly unsaturated PCs (36:5, 36:6, 38:6, 40:6, 40:7) and an increase in plasmanyl-PCs (36:5, 38:5), lyso-PCs (16:1, 18:1, 22:4) and cholesteryl esters (CEs) (16:0, 18:0, 20:4) in fish from polluted sites. These lipid profiles were indicative of oxidative stress and dysregulation of cholesterol homeostasis in fish from polluted sites. This methodology represents a promising tool for the development of novel noninvasive diagnostic methods based on muscle tissue biopsies to assess the effects of water pollution in wildlife. | es_ES |
dc.description.sponsorship | Anna Marqueño acknowledges a predoctoral fellowship BES-2015-074842. This work was financed by Ministerio de Ciencia e Innovación, under the project CGL2014-52144-P. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | American Chemical Society | es_ES |
dc.relation | info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CGL2014-52144-P | es_ES |
dc.relation.isversionof | Postprint | es_ES |
dc.rights | openAccess | en_EN |
dc.subject | Liquid chromatography | es_ES |
dc.subject | UPLC-HRMS | es_ES |
dc.subject | Fish | es_ES |
dc.subject | Wastewaters | es_ES |
dc.title | Skeletal Muscle Lipidomics as a New Tool to Determine Altered Lipid Homeostasis in Fish Exposed to Urban and Industrial Wastewaters | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.1021/acs.est.9b02064 | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | https://doi.org/10.1021/acs.est.9b02064 | es_ES |
dc.embargo.terms | 2020-06-17 | es_ES |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | es_ES |
dc.relation.csic | Sí | es_ES |
oprm.item.hasRevision | no ko 0 false | * |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003329 | es_ES |
dc.contributor.orcid | Porte, Cinta [0000-0002-3940-6409] | es_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | With Fulltext | - |
item.languageiso639-1 | en | - |
Aparece en las colecciones: | (IDAEA) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
Skeletal Muscle Lipidomics as a New Tool to Determine Altered Lipid Homeostasis in Fish Exposed to Urban and Industrial Wastewaters.pdf | Artículo principal | 1,09 MB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
19
checked on 13-abr-2024
WEB OF SCIENCETM
Citations
17
checked on 24-feb-2024
Page view(s)
284
checked on 22-abr-2024
Download(s)
376
checked on 22-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.