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Title

Bioactive constituents from transformed root cultures of Nepeta teydea

AuthorsFraga, Braulio M. ; González-Coloma, Azucena ; Alegre-Gómez, Sergio; López-Rodríguez, Matías; Amador, Leonardo J.; Díaz, Carmen E.
KeywordsLamiaceae
Teydeadione
Biological activity
Phenolic compounds
Teydealdehyde
Nepeta teydea
Triterpenes
Transformed root cultures
Sesquiterpenes
(-)-Cinalbicol
Diterpenes
Issue DateJan-2017
PublisherElsevier
CitationPhytochemistry 133: 59-68 (2017)
AbstractA phytochemical study of an extract from transformed root cultures of Nepeta teydea, induced by Agrobacterium rhizogenes, led to the isolation of the following new compounds: the sesquiterpene (-)-cinalbicol, the diterpene teydeadione (6,11,14-trihydroxy-12-methoxy-abieta-5,8,11,13,15-penten-7-one), a degraded C23-triterpene (teydealdehyde) and three fatty acid esters of lanosta-7,24-dien-3β-ol. The propyl ester of rosmarinic acid was also isolated for the first time from a natural source. In addition, two dehydroabietane diterpenes, eight triterpenes and eighteen known phenolic compounds were obtained. The antifeedant, cytotoxic and phytotoxic activities of the isolated compounds have also been investigated.
Publisher version (URL)https://doi.org/10.1016/j.phytochem.2016.10.008
URIhttp://hdl.handle.net/10261/185077
DOIhttp://dx.doi.org/10.1016/j.phytochem.2016.10.008
ISSN0031-9422
E-ISSN1873-3700
Appears in Collections:(IPNA) Artículos
(ICA) Artículos
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