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Título

Monoglyceride surfactants from arginine: synthesis and biological properties

AutorPérez, Lourdes; Pinazo Gassol, Aurora; García Ramón, María Teresa ; Morán, María del Carmen; Infante, María Rosa
Palabras claveMonoglyceride surfactants
Dicationic arginine based surfactants
1-acyl-3-O-(L-arginyl)-rac-glycerol·2HCl
Antimicrobial properties
Fecha de publicación19-feb-2004
EditorRoyal Society of Chemistry (Great Britain)
CitaciónNew Journal of Chemistry 28(11): 1326-1334 (2004)
ResumenA novel family of dicationic arginine-monoglyceride surfactants, 1-acyl-3-O-(L-arginyl)-rac-glycerol·2HCl, was synthesised and characterised. They have one alkyl chain of with length in the range of C10–C14 attached to the glycerol though esters bonds and a dicationic polar head from the arginine. Structurally they can be regarded as analogues of the monoglycerides, widely used as emulsifiers in the food and in the pharmaceutical industry. The introduction of the basic amino acid arginine into the monoglycerides increases the solubility of these compounds and improves their antimicrobial activity. Moreover, the acute toxicity of these surfactants against Daphnia magna is clearly lower than the toxicity reported for conventional cationic surfactants.
Descripción9 pages, 9 figures, 5 tables.-- Printed version published Nov 2004.
Versión del editorhttp://dx.doi.org/10.1039/b405733c
URIhttp://hdl.handle.net/10261/18380
DOI10.1039/b405733c
ISSN1144-0546
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