English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/182785
Share/Impact:
Statistics
logo share SHARE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Title

Interplay between extracellular matrix components of Pseudomonas putida biofilms

AuthorsMartínez-Gil, M.; Quesada, José Miguel; Ramos-González, María Isabel; Soriano, María Isabel; de Cristóbal, R.E.; Espinosa-Urgel, Manuel
KeywordsExopolysaccharide
Colony morphology
c-di-GMP
Expression
Surface protein
Issue Date2013
PublisherElsevier
CitationResearch in Microbiology 164: 382- 389 (2013)
AbstractThe extracellular matrix of bacterial biofilms has at least two key functions: to serve as a structural scaffold for the multicellular community, and to play a protective role against external stress. In this work, we report a compensatory effect whereby Pseudomonas putida reacts to the lack of either of the two main surface proteins involved in biofilm formation, LapA and LapF, by increasing expression and production of a species-specific EPS. Elevated levels of the second messenger molecule cyclic di-GMP alter the balance of extracellular matrix components, and the phenotypes of lapA and lapF mutants under these conditions are indicative of direct interactions taking place between large secreted proteins and exopolysaccharides. Our data suggest the existence of a mechanism by which bacteria would sense alterations in the composition of the extracellular matrix, leading to changes in expression of the different elements. © 2013 Institut Pasteur.
URIhttp://hdl.handle.net/10261/182785
Identifiersdoi: 10.1016/j.resmic.2013.03.021
issn: 0923-2508
Appears in Collections:(EEZ) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.