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http://hdl.handle.net/10261/182227
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Thorne, Claire | es_ES |
dc.contributor.author | Turkova, Anna | es_ES |
dc.contributor.author | Indolfi, Giuseppe | es_ES |
dc.contributor.author | Venturini, Elisabetta | es_ES |
dc.contributor.author | Giaquinto, Carlo | es_ES |
dc.contributor.author | Goetghebuer, Tessa | es_ES |
dc.contributor.author | Hainaut, Marc | es_ES |
dc.contributor.author | Van der Kelen, Evelyne | es_ES |
dc.contributor.author | Königs, Christoph | es_ES |
dc.contributor.author | Mantzsch, Kathleen | es_ES |
dc.contributor.author | Baumann, Ulrich | es_ES |
dc.contributor.author | de Martino, Maurizio | es_ES |
dc.contributor.author | Galli, Luisa | es_ES |
dc.contributor.author | Giacomet, Vania | es_ES |
dc.contributor.author | Nicolini, Laura Ambra | es_ES |
dc.contributor.author | Del Puente, Filippo | es_ES |
dc.contributor.author | Gabiano, Clara | es_ES |
dc.contributor.author | Guarino, Alfredo | es_ES |
dc.contributor.author | Martinazzi, Silvia | es_ES |
dc.contributor.author | Miniaci, Angela | es_ES |
dc.contributor.author | Dobsz, Sabina | es_ES |
dc.contributor.author | Marczynska, Magdalena | es_ES |
dc.contributor.author | Ene, Luminita | es_ES |
dc.contributor.author | Duiculescu, Dan | es_ES |
dc.contributor.author | Miloenko, Milana | es_ES |
dc.contributor.author | Dodonov, Konstantin | es_ES |
dc.contributor.author | Latysheva, Inga | es_ES |
dc.contributor.author | Voronin, Evgeny | es_ES |
dc.contributor.author | Rojo, Pablo | es_ES |
dc.contributor.author | Ramos, José Tomás | es_ES |
dc.contributor.author | Navarro Gómez, María Luisa | es_ES |
dc.contributor.author | Jiménez de Ory, Santiago | es_ES |
dc.contributor.author | Sainz, Talia | es_ES |
dc.contributor.author | Mellado, Maria Jose | es_ES |
dc.contributor.author | García, Miluca | es_ES |
dc.contributor.author | Pérez, Carlos | es_ES |
dc.contributor.author | Moreno-Pérez, David | es_ES |
dc.contributor.author | Nuñez, Esmeralda | es_ES |
dc.contributor.author | Gracia, Mercedes | es_ES |
dc.contributor.author | Terol, Pedro | es_ES |
dc.contributor.author | Neth, Olaf | es_ES |
dc.contributor.author | Falcón Neyra, Lola | es_ES |
dc.contributor.author | Otero, Carmen | es_ES |
dc.contributor.author | Rincón, Elena | es_ES |
dc.contributor.author | Gavilán, César | es_ES |
dc.contributor.author | López, Carmen | es_ES |
dc.contributor.author | Santos, Juan Luis | es_ES |
dc.contributor.author | Couceiro, José | es_ES |
dc.contributor.author | Noguera-Julián, Antoni | es_ES |
dc.contributor.author | Fortuny, Claudia | es_ES |
dc.contributor.author | Soler-Palacín, Pere | es_ES |
dc.contributor.author | Espiau, María | es_ES |
dc.contributor.author | Mur, Antonio | es_ES |
dc.contributor.author | Coll, María T. | es_ES |
dc.contributor.author | Valmanya, María T. | es_ES |
dc.contributor.author | Mayol, Lluis | es_ES |
dc.contributor.author | Méndez, María José | es_ES |
dc.contributor.author | Rodrigo, Carlos | es_ES |
dc.contributor.author | Escribano, Joaquín | es_ES |
dc.contributor.author | Rius, Neus | es_ES |
dc.contributor.author | Rovira, Núria | es_ES |
dc.contributor.author | Calavia, Olga | es_ES |
dc.contributor.author | García, Lourdes | es_ES |
dc.contributor.author | Pineda, Valentí | es_ES |
dc.contributor.author | Soriano-Arandes, Antoni | es_ES |
dc.contributor.author | Rudin, Christoph | es_ES |
dc.contributor.author | Duppenthaler, Andrea | es_ES |
dc.contributor.author | Judd, Ali | es_ES |
dc.contributor.author | Malyuta, Ruslan | es_ES |
dc.contributor.author | Volokha, Alla | es_ES |
dc.contributor.author | Raus, Irina | es_ES |
dc.contributor.author | Kaleeva, T. | es_ES |
dc.contributor.author | Baryshnikova, Y. | es_ES |
dc.contributor.author | Soloha, Svetlana | es_ES |
dc.contributor.author | Bashkatova, N. | es_ES |
dc.contributor.author | Glutshenko, O. | es_ES |
dc.contributor.author | Ruban, Z. | es_ES |
dc.contributor.author | Primak, Natalia | es_ES |
dc.contributor.author | Kiseleva, Galina | es_ES |
dc.date.accessioned | 2019-05-23T14:49:37Z | - |
dc.date.available | 2019-05-23T14:49:37Z | - |
dc.date.issued | 2017-01 | - |
dc.identifier.citation | AIDS 31(1): 127-135 (2017) | es_ES |
dc.identifier.issn | 0269-9370 | - |
dc.identifier.uri | http://hdl.handle.net/10261/182227 | - |
dc.description.abstract | [Objective] To characterize children, adolescents and young adults infected with HIV/hepatitis C virus (HCV) vertically or before age of 18 years and living in Europe regarding mode of acquisition, HCV genotype, clinical status and treatment. | es_ES |
dc.description.abstract | [Design] Retrospective, cross-sectional study using pooled data from 11 European paediatric HIV cohorts. | es_ES |
dc.description.abstract | [Methods] Patients aged more than 18 months and less than 25 years, with HIV/HCV acquired vertically or in childhood, were included. Anonymized individual patient data were collected using a standard protocol and modified HIV Cohorts Data Exchange Protocol. | es_ES |
dc.description.abstract | [Results] Of 229 patients included, 142 (62%) had vertically acquired infection. Median age at last follow-up was 16.2 years. Most children had HCV genotype 1 (101/184, 55%) or 3 (57/184, 31%). One-fifth (46/214) had a previous AIDS diagnosis (data missing on prior AIDS diagnoses for 15). At their last clinic visit, 70% (145/208) had no/mild immunosuppression (Centers for Disease Control and Prevention stage 1), and 131 of 179 on antiretroviral therapy had undetectable HIV RNA (assay thresholds varied from <20 to <150 copies/ml). Overall, 42% (86/204) had hepatomegaly in the previous year, and 55% (116/213) had alanine aminotransferase more than 40 IU/l at their last test. Of 97 patients with transient elastography, 12 had results more than 9 kPa; this was associated with duration of HCV infection (P = 0.033), but not with CD4+ cell count, antiretroviral therapy use or sex in univariable analysis. Of 17 patients with liver biopsies, six had bridging fibrosis and one had cirrhosis. Twenty-five (11%) had been treated successfully for HCV. | es_ES |
dc.description.abstract | [Conclusion] The high proportion of patients with progressive liver disease underscores the need for close monitoring and earlier and more effective HCV treatment. | es_ES |
dc.description.sponsorship | This work was supported by funding from the EU Seventh Framework Programme (FP7/2007–2013) under EuroCoord grant agreement [no. 260694] and additional funding from Janssen. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Lippincott Williams & Wilkins | es_ES |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/260694 | es_ES |
dc.rights | closedAccess | es_ES |
dc.subject | Coinfection | es_ES |
dc.subject | Hepatitis C | es_ES |
dc.subject | HIV | es_ES |
dc.subject | Paediatric | es_ES |
dc.subject | Vertical infection | es_ES |
dc.title | Coinfection with HIV and hepatitis C virus in 229 children and young adults living in Europe | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.1097/QAD.0000000000001285 | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | https://doi.org/10.1097/QAD.0000000000001285 | es_ES |
dc.identifier.e-issn | 1473-5571 | - |
dc.contributor.funder | European Commission | es_ES |
dc.contributor.funder | Janssen Biotech | es_ES |
dc.relation.csic | Sí | es_ES |
oprm.item.hasRevision | no ko 0 false | * |
dc.identifier.funder | http://dx.doi.org/10.13039/100005565 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100000780 | es_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
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