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A baseline metabolomic signature is associated with immunological CD4+ T-Cell recovery after 36 months of art in HIV-infected patients

AuthorsRodríguez-Gallego, Esther; Gómez, Josep; Pacheco, Yolanda M. ; Peraire, Joaquim; Viladés, Consuelo; Beltrán-Debón, Raúl; Mallol, Roger; López-Dupla, Miguel; Veloso, Sergi; Alba, Verónica; Blanco, Julià; Rull, Anna; Cañellas, Nicolau; Leal, Manuel; Correig, X.; Domingo, Pere; Vidal, Francesc
Issue DateAug-2018
CitationAtherosclerosis 275: e33 (2018)
AbstractPoor immunological recovery in treated HIV-infected patients is associated with greater morbidity and mortality. To date, predictive biomarkers of this incomplete immune reconstitution have not been established. We aimed to identify a baseline metabolomic signature associated with a poor immunological recovery after ART in order to envisage the underlying mechanistic pathways that influence the treatment response.
Publisher version (URL)https://doi.org/10.1016/j.atherosclerosis.2018.06.085
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