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Transinfected lymphocytes for anti-tumor therapy

Other TitlesLinfocitos transinfectados para terapia anti-tumoral
AuthorsVeiga Chacón, Esteban; Cruz-Adalia, Aránzazu; Ramírez Santiago, Guillermo; Alarcón, Balbino ; Sánchez Madrid, Francisco
Issue Date16-Feb-2017
CitationWO2017025657 A1
Abstract[EN] The present invention relates to lymphocytes, preferably that have been transinfected from dendritic cells with a bacterium, preferably CD4+ T cells, preferably Listeria monocytogenes, wherein said bacterium comprises a tumor peptide. It also relates to the use of lymphocytes for therapy and/or treatment of solid tumors, preferably melanoma, the kit or device that comprises same for this purpose. Furthermore, it also refers to the transinfection method thereof.
[ES] La presente invención se refiere a linfocitos, preferiblemente que han sido transinfectados desde células dendríticas con una bacteria, preferiblemente linfocitos T CD4+, preferiblemente Listeria monocytogenes, donde dicha bacteria comprende un péptido tumoral. También se refiere al uso de los linfocitos para terapia y/o tratamiento de tumores sólidos, preferiblemente melanoma, al kit o dispositivo que los comprende para dicho fin. Además, también se refiereal método de transinfección de los mismos.
Appears in Collections:(CBM) Patentes
(CNB) Patentes
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