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Title: | P38 inhibitors for the treatment and prophylaxis of liver cancer |
Other Titles: | Inhibidores de la P38 para el tratamiento y profilaxis del cáncer de hígado |
Authors: | Sabio, Guadalupe; Tomás Loba, Antonia; Martínez, Ana ![]() ![]() |
Issue Date: | 15-Dec-2016 |
Citation: | WO2016198698 A2 |
Abstract: | [EN] The present invention provides p38 inhibitors which are useful for the treatment and/or prophylaxis of liver cancer. In particular, the present invention provides compounds capable of inhibiting the intracellular expression of the p38 gamma protein in the hepatocytes of a subject relative to that observed in the absence of the compound, for use in the therapeutic treatment of liver cancer. [ES] La presente invención proporciona inhibidores de p38 que son útiles para el tratamiento y / o la profilaxis del cáncer de hígado. En particular, la presente invención proporciona compuestos capaces de inhibir la expresión intracelular de la proteína gamma p38 en los hepatocitos de un sujeto con relación a la observada en ausencia del compuesto, para uso en el tratamiento terapéutico del cáncer de hígado. |
URI: | http://hdl.handle.net/10261/177465 |
Appears in Collections: | (CIB) Patentes |
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WO2016198698A2.pdf | 4,92 MB | Adobe PDF | ![]() View/Open |
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