Monoclonal antibodies against bambi and use for the treatment of inflammatory diseases

Abstract

[EN] The present invention relates to a reverse two-hybrid method for the identification of missense-type mutations that prevent the binding of two interacting proteins. The invention also describes gene constructs that can be used in the method of the invention, as well as the host cell which comprises said constructs and can be used in the method of the invention.

[ES] Anticuerpos monoclonales frente a BAMBI y uso para tratamiento de enfermedades inflamatorias. La presente invención se refiere a anticuerpos monoclonales específicos frente a un péptido de la proteína BAMBI, así como a sus usos y métodos que los comprenden. Preferiblemente los anticuerpos se utilizan para el tratamiento de enfermedades autoinmunes.