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dc.contributor.authorFornaguera, Cristinaes_ES
dc.contributor.authorSoláns, Conxitaes_ES
dc.identifier.citationInternational Journal of Polymer Science 2018: 6387826 (2018)es_ES
dc.description.abstractAdvances in polymeric nanoparticles as novel nanomedicines have opened a new class of diagnostic and therapeutic tools for many diseases. However, although the benchtop research studies in the nanoworld are numerous, their translation to currently marketed products is still limited. This lack of transference can be attributed, among other factors, to problems with nanomedicine characterization. Characterization techniques at the nanoscale could be divided in three categories: characterization of physicochemical properties (e.g., size and surface charge), characterization of nanomaterials interactions with biological components (e.g., proteins from the blood), and analytical characterization and purification methods. Currently available literature of this last group only describes methodologies applied for a specific type of nanomaterial or even methods used for bulk materials, which are not completely applicable to nanomaterials. For this reason, the current review aims to become a scholastic guide for those scientists starting in the nanoworld, giving them a description of analytical characterization techniques aimed to analyze polymers forming nanoparticles and possible forms to purify them before being used in preclinical and clinical applications. © 2018 Cristina Fornaguera and Conxita Solans.es_ES
dc.description.sponsorshipThis work was funded by Spanish Ministry of Economy and Competitivity, MINECO (grant CTQ2014-52687) and Generalitat de Catalunya (grant 2014-SGR-1655). CIBER-BBN is an initiative funded by the VI National R&D&I Plan 2008–2011, Iniciativa Ingenio 2010, Consolider Program, CIBER Actions and financed by the Instituto de Salud Carlos III with assistance from the European Regional Development Fund. Cristina Fornaguera is grateful to MINECO for their PTQ2015 grant.es_ES
dc.publisherHindawi Publishing Corporationes_ES
dc.relation.isversionofPublisher's versiones_ES
dc.subjectAtomic forcees_ES
dc.titleAnalytical Methods to Characterize and Purify Polymeric Nanoparticleses_ES
dc.description.peerreviewedPeer reviewedes_ES
dc.contributor.funderMinisterio de Economía y Competitividad (España)es_ES
oprm.item.hasRevisionno ko 0 false*
dc.contributor.orcidFornaguera, Cristina [0000-0002-7014-3213]es_ES
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