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dc.contributor.authorDelgado López, José Manueles_ES
dc.contributor.authorGómez-Morales, J.es_ES
dc.contributor.authorFernández Penas, Raqueles_ES
dc.contributor.authorIafisco, Michelees_ES
dc.contributor.authorTampieri, Annaes_ES
dc.contributor.authorPanseri, Silviaes_ES
dc.identifier.citationUS10105390 B2es_ES
dc.description.abstractProcess for obtaining fluoride-doped citrate-coated amorphous calcium phosphate nanoparticles. This material has applications in biomedicine due to its biodegradability and bioactivity; it also promotes cell adhesion and osteogeneration. In dentistry, it may be used in toothpastes, mouthwashes, chewing gums, gels and fluoride varnishes as a remineralising agent of dentine and enamel. It is based on two solutions formed by calcium chloride and sodium citrate on the one hand, and by sodium monohydrogenophosphate and sodium carbonate with a fluoride compound on the other, which are mixed at room temperature. The process is eco-efficient and eco-friendly, as it does not leave any acid residue; it consists of a single stage and it is the first time that an amorphous calcium phosphate coated with citrate and doped with fluoride, which enhances its remineralising action, is obtained.es_ES
dc.titleProcess for obtaining fluoride-doped citrate-coated amorphous calcium phosphate nanoparticleses_ES
dc.title.alternativeProcedimiento de obtención de nanopartículas de fosfato de calcio amorfo recubiertas de citrato y dopadas con flúores_ES
dc.typesolicitud de patentees_ES
dc.description.peerreviewedPeer reviewedes_ES
dc.description.assigneeConsejo Superior de Investigaciones Científicas (España), Consiglio Nazionale delle Ricerchees_ES
dc.relation.patentfamilyES2557183 B1 (2016-01-22)-
dc.relation.patentfamilyES2557183 A1 (2016-01-22)-
dc.relation.patentfamilyWO2016012452 A1 (2016-01-28)-
dc.relation.patentfamilyEP3177273 A1 (2017-06-14)-
dc.relation.patentfamilyUS2017209491 A1 (2017-07-27)-
dc.relation.patentfamilyBR112017001426 A2 (2017-11-28)-
dc.relation.patentfamilyCN106999355 A (2017-08-01)-
dc.relation.patentfamilyKR20170052572 A (2017-05-12)-
dc.relation.patentfamilyRU2017101869 A (2018-08-21)-
dc.description.kindB2 Patente con examen previoes_ES
oprm.item.hasRevisionno ko 0 false*
Appears in Collections:(IACT) Patentes
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