Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/173169
Share/Export:
logo share SHARE logo core CORE BASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE

Invite to open peer review
Title

Bone tissue scaffolds based on antimicrobial SiO2-Na2O-Al2O3-CaO-B2O3 glass

AuthorsEsteban-Tejeda, Leticia CSIC; Zheng, Kai; Prado, Catuxa CSIC ORCID; Cabal, Belén CSIC ORCID ; Torrecillas, Ramón CSIC ORCID CVN; Boccaccini, Aldo R.; Moya, J. S. CSIC
KeywordsAntimicrobial
Soda-lime glass-ceramics
Scaffold
Issue Date2016
PublisherElsevier
CitationJournal of Non-Crystalline Solids 432A: 73-80 (2016)
AbstractThis paper reports the fabrication, microstructural characterization, mechanical properties and antimicrobial activity of scaffolds obtained from a soda-lime glass powder constituted by micro-spheres belonging to the SiO-NaO-AlO-CaO - BO system. Scaffolds with a porosity > 90% were fabricated using the foam replication method in the temperature range of 750-850 °C. The highest compressive strength value (0.2 MPa) was obtained for the scaffolds sintered at 850 °C. The observed mechanical properties were rationalized considering the scaffold singular microstructure of the struts constituted by a dense packing of microspheres ranging from 4 to 30 μm interlocked by nepheline needle-like crystals. The antimicrobial test was performed against three different microorganisms: Escherichia coli, Staphylococcus aureus and Candida krusei (yeast). A 45S5 Bioglass® scaffold was also tested for comparison. A window glass scaffold was used as control. In all cases a safe disinfection was obtained (reduction > 99.9% = log of reduction > 3). The antimicrobial activity was found to be similar to that of 45S5 Bioglass® based scaffolds. However, the soda-lime scaffold sintered at 850 °C exhibited a higher antimicrobial activity (log of reduction > 5 = reduction > 99.999%) against C. krusei, which is a microorganism resistant to multiples biocides, than the Bioglass® scaffold (log of reduction < 2 = reduction > 99.0%).
URIhttp://hdl.handle.net/10261/173169
DOI10.1016/j.jnoncrysol.2015.05.040
Identifiersdoi: 10.1016/j.jnoncrysol.2015.05.040
issn: 0022-3093
e-issn: 1873-4812
Appears in Collections:(ICMM) Artículos
(CINN) Artículos




Files in This Item:
File Description SizeFormat
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
View/Open
Show full item record

CORE Recommender

SCOPUSTM   
Citations

19
checked on May 15, 2024

WEB OF SCIENCETM
Citations

16
checked on Feb 27, 2024

Page view(s)

256
checked on May 25, 2024

Download(s)

101
checked on May 25, 2024

Google ScholarTM

Check

Altmetric

Altmetric


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.