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dc.contributor.authorAlehosseini, Alies_ES
dc.contributor.authorGómez del Pulgar, Eva M.es_ES
dc.contributor.authorFabra, María Josées_ES
dc.contributor.authorGómez-Mascaraque, Laura G.es_ES
dc.contributor.authorBenítez Páez, Alfonsoes_ES
dc.contributor.authorSarabi-Jama, M.es_ES
dc.contributor.authorGhorani, B.es_ES
dc.contributor.authorLópez-Rubio, Amparoes_ES
dc.date.accessioned2018-11-23T11:03:25Z-
dc.date.available2018-11-23T11:03:25Z-
dc.date.issued2018-08-20-
dc.identifier.citationFood Hydrocolloids 87: 487-496 (2019)es_ES
dc.identifier.issn0268-005X-
dc.identifier.urihttp://hdl.handle.net/10261/172589-
dc.description.abstractThis work reports on a simple, fast and food-grade encapsulation approach with potential for probiotic protection, which consists on the formation of agarose-based hydrogel particles. These were generated by the supramolecular self-assembly of the probiotic-containing carbohydrate solutions by dripping them into a biphasic bath with an upper oil layer, which acted as the particle-forming antisolvent, and a lower aqueous layer, where the hydrogel particles were collected. This technique, which we have named “oil-induced biphasic hydrogel particle formation”, has been used to encapsulate the sensitive strain Bifidobacterium pseudocatenulatum CECT 7765. In order to avoid agarose gelling at 40 °C before the encapsulation process, this seaweed-derived carbohydrate was combined with other hydrocolloids (alginate, whey protein concentrate, and gelatin), and the obtained probiotic-containing hydrogel particles were subsequently freeze-dried. The protection ability of this method versus directly freeze-drying the probiotic-containing solutions was demonstrated during storage and simulated in-vitro digestion. Both the formation of a continuous layer surrounding the bacteria and the optimal combination of materials (agarose providing suitable oxygen barrier and WPC with proven probiotic affinity) rendered encapsulation systems keeping viability levels required for commercial applications.es_ES
dc.description.sponsorshipA. Alehosseini received a scholarship by the Ministry of Science, Research and Technology of Iran. M.J. Fabra is recipient of a Ramon y Cajal (RYC-2014-158) contract from the Spanish Ministry of Economy, Industry and Competitiveness. The authors would like to thank the Spanish MINECO project AGL2015-63855-C2-1 and the Agencia Estatal de Investigación for financial support. ABP and EMGP are contracted with the grant no 613979 of the European Union's Seventh Framework Program (MyNewGut).es_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.relationinfo:eu-repo/grantAgreement/EC/FP7/613979es_ES
dc.relationinfo:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2015-63855-C2-1es_ES
dc.relation.isversionofPostprintes_ES
dc.rightsopenAccessen_EN
dc.subjectEncapsulationes_ES
dc.subjectProbioticses_ES
dc.subjectAgarosees_ES
dc.subjectFreeze-dryinges_ES
dc.subjectGITes_ES
dc.subjectWPCes_ES
dc.titleAgarose-based freeze-dried capsules prepared by the oil-induced biphasic hydrogel particle formation approach for the protection of sensitive probiotic bacteriaes_ES
dc.typeartículoes_ES
dc.identifier.doi10.1016/j.foodhyd.2018.08.032-
dc.description.peerreviewedPeer reviewedes_ES
dc.relation.publisherversionhttps://doi.org/10.1016/j.foodhyd.2018.08.032es_ES
dc.embargo.terms2019-08-20es_ES
dc.rights.licensehttp://creativecommons.org/licenses/by-nc-nd/4.0/es_ES
dc.contributor.funderMinisterio de Economía y Competitividad (España)es_ES
dc.contributor.funderMinistry of Science, Research, and Technology (Iran)es_ES
dc.contributor.funderEuropean Commissiones_ES
dc.relation.csices_ES
oprm.item.hasRevisionno ko 0 false*
dc.identifier.funderhttp://dx.doi.org/10.13039/501100000780es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100003329es_ES
dc.type.coarhttp://purl.org/coar/resource_type/c_6501es_ES
item.openairetypeartículo-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextopen-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
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