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Effects of dietary AGEs in the gut microbiota composition

AuthorsPérez-Burillo, Sergio; Pastoriza, Silvia; Rufián Henares, J. A.; Delgado Andrade, Cristina
Issue Date2017
PublisherCRC Press
Taylor & Francis
CitationDietary AGE and Their Role in Health and Disease: 239-244 (2017)
AbstractKey Points: • Microbiota modulators are molecules, which pass through the gastrointestinal tract totally or partially intact. • Advanced glycation end products (AGEs), largely present in the Western diet, are structureswith decreased digestibility, thus potential modulators of colon microbiota. • Human and animal trials demonstrate AGEs are able to modulate the intestinal microbiota composition. • The specific effects are associated with their particular chemical structure and dietary amounts. • Negative actions seem to be essentially linked to their ability to activate proinflammatory routes within the enterocyte, leading to different pathological processes.
DescriptionCap. 19: Contents: -19.1 Introduction 239, -19.2 AGE Absorption and Their Role as Substrate for Gut Microbiota 240; -19.3 Studies Supporting the Ability of AGE to Act as Microbiota Modulators 241; 19.4 Linkage Between Microbiota Modulation by AGEs and Gastrointestinal Diseases 243; -19.5 Conclusions 243; -References.
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