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http://hdl.handle.net/10261/172555
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dc.contributor.author | Sharif, Niloufar | - |
dc.contributor.author | Golmakani, Mohammad-Taghi | - |
dc.contributor.author | Niakousari, Mehrdad | - |
dc.contributor.author | Hosseini, Seyed Mohammad Hashem | - |
dc.contributor.author | Ghorani, Behrouz | - |
dc.contributor.author | López-Rubio, Amparo | - |
dc.date.accessioned | 2018-11-22T14:23:37Z | - |
dc.date.available | 2018-11-22T14:23:37Z | - |
dc.date.issued | 2018-11-07 | - |
dc.identifier.citation | Nanomaterials 8(11): 919 (2018) | - |
dc.identifier.uri | http://hdl.handle.net/10261/172555 | - |
dc.description.abstract | In this work, hybrid gliadin electrospun fibers containing inclusion complexes of ferulic acid (FA) with hydroxypropyl-beta-cyclodextrins (FA/HP-β-CD-IC) were prepared as a strategy to increase the stability and solubility of the antioxidant FA. Inclusion complex formation between FA and HP-β-CD was confirmed by Fourier transform infrared spectroscopy (FTIR), differential scanning calorimeter (DSC), and X-ray diffraction (XRD). After adjusting the electrospinning conditions, beaded-free fibers of gliadin incorporating FA/HP-β-CD-IC with average fiber diameters ranging from 269.91 ± 73.53 to 271.68 ± 72.76 nm were obtained. Control gliadin fibers containing free FA were also produced for comparison purposes. The incorporation of FA within the cyclodextrin molecules resulted in increased thermal stability of the antioxidant compound. Moreover, formation of the inclusion complexes also enhanced the FA photostability, as after exposing the electrospun fibers to UV light during 60 min, photodegradation of the compound was reduced in more than 30%. Moreover, a slower degradation rate was also observed when compared to the fibers containing the free FA. Results from the release into two food simulants (ethanol 10% and acetic acid 3%) and PBS also demonstrated that the formation of the inclusion complexes successfully resulted in improved solubility, as reflected from the faster and greater release of the compounds in the three assayed media. Moreover, in both types of hybrid fibers, the antioxidant capacity of FA was kept, thus confirming the suitability of electrospinning for the encapsulation of sensitive compounds, giving raise to nanostructures with potential as active packaging structures or delivery systems of use in pharmaceutical or biomedical applications. | - |
dc.description.sponsorship | The authors would like to thank the Spanish MINECO project AGL2015-63855-C2-1 for financial support. In addition, the authors gratefully acknowledge the financial support of the Research Affairs Office at Shiraz University (Grant #93GCU1M1981). | - |
dc.publisher | Multidisciplinary Digital Publishing Institute | - |
dc.relation | info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2015-63855-C2-1 | - |
dc.relation.isversionof | Publisher's version | - |
dc.rights | openAccess | - |
dc.subject | Gliadin | - |
dc.subject | Ferulic acid | - |
dc.subject | Hydroxypropyl-beta-cyclodextrin | - |
dc.subject | Electrospinning | - |
dc.title | Active food packaging coatings based on hybrid electrospun gliadin nanofibers containing ferulic acid/hydroxypropyl-beta-cyclodextrin inclusion complexes | - |
dc.type | artículo | - |
dc.identifier.doi | 10.3390/nano8110919 | - |
dc.description.peerreviewed | Peer reviewed | - |
dc.relation.publisherversion | https://doi.org/10.3390/nano8110919 | - |
dc.identifier.e-issn | 2079-4991 | - |
dc.date.updated | 2018-11-22T14:23:37Z | - |
dc.rights.license | http://creativecommons.org/licenses/by/4.0/ | - |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | - |
dc.contributor.funder | Shiraz University | - |
dc.relation.csic | Sí | - |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003329 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100005071 | es_ES |
dc.identifier.pmid | 30405064 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.fulltext | With Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.openairetype | artículo | - |
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nanomaterials-08-00919-v2.pdf | 2,75 MB | Adobe PDF | Visualizar/Abrir |
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