English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/171212
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Title

Associations between a Mediterranean diet pattern and inflammatory biomarkers in European adolescents

AuthorsArouca, Aline; Michels, Nathalie; Moreno, Luis A.; González-Gil, Esther; Marcos, Ascensión ; Gómez Martínez, Sonia ; Díaz, L. E. ; Widhalm, Kurt; Molnar, Denes; Manios, Yannis; Gottrand, Frederic; Kafatos, Anthony; Kersting, Mathilde; Sjöström, Michael; O, Alex de la; Ferrari, Marika; Huybrechts, Inge; González Gross, Marcela; De Henauw, Stefaan
KeywordsDiet–inflammation associations
Adolescents
Mediterranean diet
Inflammation
Issue Date2017
PublisherSpringer Nature
CitationEuropean Journal of Nutrition 57(5): 1747-1760 (2017)
Abstract[Aim]: To test whether the Mediterranean diet score and each food-subgroup is associated with inflammatory biomarkers in European adolescents. [Methods]: In 464 adolescents (13-17 years) of the European HELENA study, data were available on body composition, inflammation markers, and food intake determined by two computerized 24-h recalls. The Mediterranean diet score and its food-subgroups (Vegetables, Fruits and Nuts, Pulses, Cereal and Roots, Monounsaturated/Saturated fat ratio, Dairy, Fish, Meat and Alcohol) were evaluated. A set of inflammation-related biomarkers was measured: IL-1, IL-2, IL-4, IL-5, IL-6, IL-10, TGFß-1, TNF-¿, sVCAM-1, sICAM1, sE-selectin, white blood cells, lymphocytes, CD3, CRP, GGT, ALT, and homocysteine. Multivariate and multiple linear regression analyses were adjusted for age, sex, country, socioeconomic status, paternal and maternal education, adiposity, and smoking habits. [Results]: The Mediterranean diet score was positively associated with CRP, and negatively with sVCAM-1. The subgroups showed the following positive/negative associations: Vegetables with IL-10(+), CRP(+), CD3(+), ALT(+), lymphocytes(+), sE-selectin(-); Fruits and Nuts with IL-4(-), TNF-alpha; Pulses with IL-5(+), IL-6(+), IL-2(-); Cereals and Roots with IL-6(-), IL-10(-); Monounsaturated/Saturated-fat ratio with IL-6(+), TGFß-1(+), sVCAM-1(+boys, -girls), homocysteine(-); Dairy with IL-1(+), IL-5(+), IL-6(+), IL-10(+), TGFß-1(+), homocysteine(-); Fish with homocysteine(-); Meat with IL-2(+), IL-10(+); Alcohol with CRP(+), lymphocytes(-). Sex differences were found. [Conclusion]: Some specific food-inflammation associations were found, suggesting that diet is to a certain extent already related to inflammation in adolescents and can be used in disease prevention. Also some counterintuitive results were found, which might be due to grouping very different foods into a single group, besides considering that the human body may respond differently depending on the interaction between diet, lifestyle, genetics, biochemical individuality, age and sex.
URIhttp://hdl.handle.net/10261/171212
Identifiersdoi: 10.1007/s00394-017-1457-4
e-issn: 1436-6215
issn: 1436-6207
Appears in Collections:(ICTAN) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.