English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/171027
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
DC FieldValueLanguage
dc.contributor.authorGaya, Pilar-
dc.contributor.authorPeirotén, Ángela-
dc.contributor.authorÁlvarez Acero, Inmaculada-
dc.contributor.authorMedina, Margarita-
dc.contributor.authorLandete, José María-
dc.date.accessioned2018-10-15T09:52:40Z-
dc.date.available2018-10-15T09:52:40Z-
dc.date.issued2018-
dc.identifierdoi: 10.1016/j.jff.2017.11.008-
dc.identifierissn: 1756-4646-
dc.identifiere-issn: 2214-9414-
dc.identifier.citationJournal of Functional Foods 40: 180-186 (2018)-
dc.identifier.urihttp://hdl.handle.net/10261/171027-
dc.description.abstractHealthy effect of isoflavones consumption is attributed to their bioactive metabolites such as O-desmethylangolensin (O-DMA) produced by intestinal bacteria. Evidence from in vitro studies suggests that O-DMA has several cancer-related biological actions. Enterococcus spp. are indigenous species of the human gastrointestinal tract. Significant attention has been focused on Enterococcus faecium strains with probiotic and /or technological interest in foods. In this work, we describe the production of the bioactive isoflavones O-DMA and 6-hydroxy O-DMA by the strain E. faecium INIA P553. O-DMA was produced from dihydrodaidzein, daidzein, daidzin and formononetin, and 6-hydroxy O-DMA from dihydrogenistein, genistein and genistin with high efficiency. To our knowledge, it is the first bacterium with probiotic potential capable of producing O-DMA and 6-hydroxy O-DMA. Therefore, this strain shows potential applications in biotechnology in functional foods and as probiotic.-
dc.description.sponsorshipThis work was supported by project RM2012-00004-00-00 from the Spanish Ministry of Economy and Competitiveness (MINECO, Madrid, Spain). J.M. Landete has a postdoctoral contract with the research program “Ramón y Cajal” (MINECO).-
dc.publisherElsevier-
dc.rightsclosedAccess-
dc.subjectEnterococcus faecium-
dc.subjectProbiotic-
dc.subjectFood-
dc.subjectO-desmethylangolensin-
dc.subjectIsoflavones-
dc.titleProduction of the bioactive isoflavone O-desmethylangolensin by Enterococcus faecium INIA P553 with high efficiency-
dc.typeArtículo-
dc.date.updated2018-10-15T09:52:41Z-
dc.description.versionPeer Reviewed-
dc.language.rfc3066eng-
dc.contributor.funderMinisterio de Economía y Competitividad (España)-
dc.relation.csic-
dc.identifier.funderhttp://dx.doi.org/10.13039/501100003329es_ES
Appears in Collections:(ICTAN) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
View/Open
Show simple item record
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.