English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/169752
COMPARTIR / IMPACTO:
Estadísticas
logo share SHARE   Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Título

Engineering and monitoring cellular barrier models

AutorYeste, Jose; Illa, Xavi; Alvarez, Mar; Villa, Rosa
Fecha de publicación12-sep-2018
EditorBioMed Central
CitaciónJournal of Biological Engineering. 2018 Sep 12;12(1):18
ResumenAbstract Epithelia and endothelia delineate tissue compartments and control their environments by regulating the passage of ions and solutes. This barrier function is essential for the development and maintenance of multicellular organisms, and its dysfunction is associated with numerous human diseases. Recent advances in biomaterials and microfabrication technologies have evolved in vitro approaches for modelling biological barriers. Current microphysiological systems have become more efficient and reliable in mimicking the cell microenvironment. Additionally, methods for the quantification of barrier permeability have long provided significant insight into their underlying mechanisms. In this review, we outline the current techniques to quantify the barrier function of engineered tissues, and we also give an overview of recent microphysiological systems of biological barriers that emulate the microenvironment and microarchitecture of native tissues.
URIhttps://doi.org/10.1186/s13036-018-0108-5
http://hdl.handle.net/10261/169752
Aparece en las colecciones: Colección Biomed Central-Chemistry Central-Springer Open
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
13036_2018_Article_108.pdf4,46 MBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.