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| Título: | CD53 |
Autor: | Lazo, Pedro A. CSIC ORCID ; Yunta, M.; Barcia, R. | Palabras clave: | CD53 deficiency Major histocompatibility complex class Human leukocyte antigen CD53 ligation Homotypic adhesion |
Fecha de publicación: | 2017 | Editor: | Springer Nature | Citación: | Encyclopedia of Signaling Molecules: 566-1-1-566-1-7 (2017) | Resumen: | CD53 is one of the least characterized members of the tetraspanin family. CD53 is integrated in the tetraspanin web, and sends intracellular signals, directly or indirectly via PKC, AKT, and g-glutamyl transpeptidase (GGT7). Its expression can affect cell survival, resistance to apoptosis, and radiation sensitivity. In B-cell development CD53 is a marker of mature B cells. In human B-cell malignancies, the pattern of tetraspanin expression identifies the developmental stage of the corresponding tumors. The pattern of tetraspanins can be used to differentiate B-cell malignancies in an individual patient with several lymphoid tumors. | URI: | http://hdl.handle.net/10261/169592 | DOI: | 10.1007/978-1-4614-6438-9_566-1 | Identificadores: | doi: 10.1007/978-1-4614-6438-9_566-1 isbn: 978-1-4614-6438-9 |
| Aparece en las colecciones: | (IBMCC) Libros y partes de libros |
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| accesoRestringido.pdf | 15,38 kB | Adobe PDF |  Visualizar/Abrir |
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