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Título: | RNA polymerase I activation and hibernation: unique mechanisms for unique genes |
Autor: | Fernández-Tornero, Carlos CSIC ORCID | Palabras clave: | Polymerase I Transcriptional regulation Ribosomal DNA RNA conformational state Enzyme activation Enzyme hibernation Cell growth |
Fecha de publicación: | 26-ene-2018 | Editor: | Taylor & Francis | Citación: | Transcription 9(4):248-254 (2018) | Resumen: | In yeast, transcription of ribosomal DNA (rDNA) by RNA polymerase I (Pol I) is regulated by unique mechanisms acting at the level of the enzyme. Under stress situations such as starvation, Pol I hibernates through dimerization. When growth conditions are restored, dimer disassembly and Rrn3 binding drive enzyme activation and subsequent recruitment to rDNA. | Descripción: | 7 p.-2 fig. | Versión del editor: | https://doi.org/10.1080/21541264.2017.1416267 | URI: | http://hdl.handle.net/10261/169347 | DOI: | 10.1080/21541264.2017.1416267 | ISSN: | 2154-1264 | E-ISSN: | 2154-1272 |
Aparece en las colecciones: | (CIB) Artículos |
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Transcription 2018.pdf | Artículo principal | 731,46 kB | Adobe PDF | Visualizar/Abrir |
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