English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/169165
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
DC FieldValueLanguage
dc.contributor.authorMatarraz, Sergio-
dc.contributor.authorAlmeida, Julia-
dc.contributor.authorFlores-Montero, Juan-
dc.contributor.authorLécrevisse, Quentin-
dc.contributor.authorGuerri, Valentina-
dc.contributor.authorLópez, Antonio-
dc.contributor.authorBarrena, Susana-
dc.contributor.authorVelden, Vincent H. J. van der-
dc.contributor.authorMarvelde, Jeroen G. te-
dc.contributor.authorDongen, J. J. M. van-
dc.contributor.authorOrfao, Alberto-
dc.identifierdoi: 10.1002/cyto.b.21219-
dc.identifiere-issn: 1552-4957-
dc.identifierissn: 1552-4949-
dc.identifier.citationCytometry Part B: Clinical Cytometry 92(3): 218-227 (2017)-
dc.description.abstractDespite diagnostic criteria are currently available for the distinct subtypes of monocytic-lineage neoplasias, a number of partially overlapping features still remain evident, which may hamper their differential diagnosis. An accurate identification and characterization of monocytic cells is of major relevance for the diagnosis and classification of these neoplasias. In this regard, as compared to other conventional techniques, flow cytometry has shown the highest sensitivity for detection of early monocytic commitment of (normal and neoplastic) bone marrow CD34 hematopoietic precursors as well as of monocytic aberrations and maturation blockades, which are frequently associated with clonal myeloid disorders. In the present paper we provide basic principles and criteria for multiparameter flow cytometry identification and characterization of bone marrow monocytic cells that contribute to an improved diagnostic and classification of monocytic lineage-associated acute leukemias in clinical settings, particularly when using the EuroFlow antibody panels.-
dc.description.sponsorshipGrant sponsor: Fundacion Cientıfica de la Asociacion Espanola Contra el Cancer (AECC), Consejerıa de Sanidad; Grant sponsor: Gerencia Regional de Salud de Castilla y Leon (SACYL); Grant number: BIO/SA24/13; Grant sponsors: Fundacion Samuel Solorzano Barruso (University of Salamanca, Spain), BlackSwan Project from the International Myeloma Foundation, North Hollywood, CA, United States of America; Grant sponsor: Cooperative Cancer Research Thematic Network (RTICC); Grant number: RD12/0036/0048; Grant sponsor: Instituto de Salud Carlos III-FEDER, Ministerio de Economia y Competitividad, Madrid, Spain.-
dc.publisherJohn Wiley & Sons-
dc.subjectAcute leukemia-
dc.subjectFlow cytometry-
dc.titleIntroduction to the diagnosis and classification of monocytic-lineage leukemias by flow cytometry-
dc.description.versionPeer Reviewed-
dc.contributor.funderInstituto de Salud Carlos III-
dc.contributor.funderMinisterio de Economía y Competitividad (España)-
dc.contributor.funderFundación Científica Asociación Española Contra el Cáncer-
dc.contributor.funderJunta de Castilla y León-
dc.contributor.funderFundación Memoria de D. Samuel Solorzano Barruso-
dc.contributor.funderInternational Myeloma Foundation-
dc.contributor.funderRed Temática de Investigación Cooperativa en Cáncer (España)-
Appears in Collections:(IBMCC) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
Show simple item record

Related articles:

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.