English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/167865
logo share SHARE   Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:


Contributions to the mathematical modelling and numerical simulation of biofilms

AuthorsLópez-Núñez, Alejandro
AdvisorVázquez, Carlos; Balsa-Canto, Eva
Issue Date2018
AbstractThe main goal of this PhD work is the development and numerical resolution of mathematical models that simulate the dynamics of bacterial biofilm systems, paying special attention to those biofilms formed by the Listeria monocytogenes, a pathogen of special relevance in food safety. A biofilm is a layer of microorganisms attached to a surface and protected by a matrix of exopolysaccharides. Biofilm structures dificult the removal of microorganisms, thus the study of the type of structures formed throughout a biofilm life cycle is key to design elimination techniques. In the present work, we develop different models that simulate the dynamics of biofilms formed by different strains of L. monocytogenes. We start with a 1D model that can be used to describe the formation of at biofilms. Afterwards, we apply the acquired knowledge to develop a 2D model capable of describing more complex structures. All this models are solved with eficient numerical methods and robust numerical techniques, such as the Level Set method, that guarantees the good behaviour of the obtained solutions. Finally, the numerical results are compared with the experimental measurements obtained in the Instituto de Investigaciones Marinas, CSIC (Vigo, Spain), and the Micalis Institute, INRA (Massy, France)
Description245 pages
Appears in Collections:(IIM) Tesis
Files in This Item:
File Description SizeFormat 
PhD_thesis_AlejandroLopez.pdf3,43 MBAdobe PDFThumbnail
Show full item record
Review this work

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.