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Title

A snail tale and the chicken embryo

AuthorsNieto, M. Ángela
KeywordsChicken embryo
Neural crest
Gastrulation
Tumour progression
Evo-devo
Issue Date2018
PublisherUniversidad del País Vasco
CitationInternational Journal of Developmental Biology 62: 117-122 (2018)
AbstractSome 25 years ago, a clone was identified that contained the chicken Slug sequences (now called Snail2 ). How could we anticipate at that time how much the chick embryo would help us to understand the ins and outs of cell migration during development and in disease? Indeed, the chick embryo helped us identify Snail2 as the first transcription factor that could induce the epithelial-mesenchymal transition (EMT), key for the migration of embryonic and cancer cells.
Publisher version (URL)http://dx.doi.org/10.1387/ijdb.170301mn
URIhttp://hdl.handle.net/10261/167844
DOI10.1387/ijdb.170301mn
ISSN0214-6282
E-ISSN1696-3547
Appears in Collections:(IN) Artículos
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