Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/16770
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | A convenient synthesis of C-22 and C-25 stereoisomers of cephalostatin north 1 side chain from spirostan sapogenins |
Autor: | Betancor, Carmen; Freire, Raimundo CSIC ORCID; Pérez-Martín, Inés CSIC ORCID ; Prangé, Thierry; Suárez, Ernesto CSIC ORCID | Fecha de publicación: | 16-mar-2002 | Editor: | American Chemical Society | Citación: | Organic Letters 4(8): 1295-1297 (2002) | Resumen: | A simple transformation of the eight-carbon side chain of a natural spirostan sapogenin into the cephalostatin north 1 spiroketal moiety is described. This methodology, based on an intramolecular hydrogen abstraction reaction promoted by alkoxy radicals, permits the synthesis of C-22 and C-25 stereoisomers of the dioxaspiro[4.4]nonane cephalostatin ring system. The acid-catalyzed isomerization of the spirocenter in the different isomers is studied. | Descripción: | 3 pages, 2 schemes.-- PMID: 11950346 [PubMed].-- Printed version published Apr 18, 2002.-- Supporting information available at: http://pubs.acs.org/doi/suppl/10.1021/ol025580e | Versión del editor: | http://dx.doi.org/10.1021/ol025580e | URI: | http://hdl.handle.net/10261/16770 | DOI: | 10.1021/ol025580e | ISSN: | 1523-7060 |
Aparece en las colecciones: | (IPNA) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
OL 2002, 4, 1295.pdf | Artículo principal | 683,45 kB | Adobe PDF | Visualizar/Abrir |
OL 2002, 4, 1295-SI.pdf | Supporting Information | 108,44 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
55
checked on 19-mar-2024
WEB OF SCIENCETM
Citations
50
checked on 28-feb-2024
Page view(s)
409
checked on 28-mar-2024
Download(s)
222
checked on 28-mar-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.