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Título: | Replicase-mediated transgenic resistance to Tobamovirus infections |
Otros títulos: | Tobamovirus replicase-mediated resistance | Autor: | Tenllado, Francisco CSIC ORCID ; Atencio, Félix A.; González-Jara, Pablo CSIC ORCID; Barajas, Daniel CSIC ORCID; Kálman, D.; Peña, L.; Díaz-Ruíz, José Ramón CSIC | Fecha de publicación: | 2002 | Editor: | Transworld Research Network (Trivandrum, India) | Citación: | Recent Research Developments in Virology 4 (2002) Eds.: J.R. Brady et al., Transworld Research Network, Vol. II | Resumen: | Plant transformation with tobamovirus gene sequences is one of a number of available strategies for the potential control of tobamovirus disease. In most cases, a complete, near immunity type of resistance can be induced in plants transformed with fragments or modified forms of the viral replicase gene and the strong resistance is exhibited against high concentrations of both virus and viral RNA inoculum. However, the transgenic plant exhibits a relatively narrow resistance spectrum, manifested only against the virus from which the transgene is derived or against very closely related virus strains. A more complete understanding of the molecular mechanisms involved in replicase-mediated transgenic resistance against tobamoviruses is needed, in order to increase its efficacy and reduce or eliminate the biosafety concerns related to its use in agriculture as a biotechnological tool for crop protection. . | Descripción: | 14 p.-3 fig. | URI: | http://hdl.handle.net/10261/167401 |
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