English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/166727
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Exportar a otros formatos:

Title

Synthesis and Characterization of a New PAMAM Metallodendrimer for Antimicrobial Modification of Cotton Fabric

AuthorsStaneva, D.; Vasileva-Tonkova, E.; Bosch, Paula ; Grozdanov, P.; Grabchev, I.
KeywordsMetallodendrimers
Scanning electron microscopy
Cotton fabric
Antimicrobial activity
1,8-naphthalimide
Issue Date2018
PublisherSpringer
CitationMacromolecular research 26: 332-340 (2018)
AbstractThe synthesis and spectral characterization of a new PAMAM metallodendrimer modified with four 4-hexylamino-1,8-naphthalimide units was described. The chemical structure of metallodendrimer has been analyzed with Fourier transform infrared spectroscopy, electronic, nuclear magnetic resonance spectroscopy, and scanning electron microscopy (SEM) analysis. The antimicrobial activity of PAMAM dendrimer and its Zn complex [Zn(D)(NO)] was investigated in agar medium and in meat-peptone broth against several pathogenic bacteria and yeasts. The antimicrobial screening showed good inhibition activity of the compounds better expressed against the test Gram-positive bacteria and yeasts. The antimicrobial efficacy of cotton fabrics treated with each of the dendrimers was evaluated, and their anti-adhesive and biofilm inhibiting potential was analyzed by SEM. The complex [Zn(D)(NO)] showed stronger antimicrobial and biofilm inhibiting abilities than those of the ligand. The cytotoxicity effect of the dendrimers was also investigated in vitro in model HEp-2 cell line.
Publisher version (URL)http://dx.doi.org/10.1007/s13233-018-6043-x
URIhttp://hdl.handle.net/10261/166727
DOIhttp://dx.doi.org/10.1007/s13233-018-6043-x
Identifiersdoi: 10.1007/s13233-018-6043-x
issn: 1598-5032
e-issn: 2092-7673
Appears in Collections:(ICTP) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.