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Title

Modeling AIPL1-defect using iPS-derived retinal progenitors from a patient Leber Congenital Amaurosis

AuthorsCerda, Berta de la ; Díez-Lloret, Andrea ; Díaz-Corrales, Francisco J. ; Valdés-Sánchez, María Lourdes; García-Delgado, Ana B.; Rodriguez-Bocanegra, Eduardo; Bhatia, Vaibhav; Ayuso, Carmen; Bhattacharya, Shom Shanker
Issue Date2016
CitationARVO 2016
AbstractPatient-derived cellular models can provide a specific tool to test new therapeutic approaches for retinal degenerative diseases. Mutations in AIPL1 are associated with Leber Congenital Amaurosis (LCA). Considering that AIPL1 protein is only expressed in photoreceptors we decided to establish a cellular model of AIPL1-LCA by differentiation of induced pluripotent stem cells (iPS) towards photoreceptor lineage.
DescriptionPóster presentado al Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), celebrado en Seattle, Washington (US) del 1 al 5 de mayo de 2016.
URIhttp://hdl.handle.net/10261/165803
Appears in Collections:(CABIMER) Comunicaciones congresos
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