English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/165322
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Exportar a otros formatos:


Cognitive decline in neuronal aging and Alzheimer's disease: Role of NMDA receptors and associated proteins

AuthorsÁvila, Jesús CSIC ORCID; Llorens-Martín, M. CSIC ORCID; Pallas-Bazarra, Noemí CSIC ORCID; Bolós, Marta; Perea, Juan Ramón; Rodríguez-Matellán, Alberto G.; Hernández, Félix
KeywordsTau proteins
Dendritic spines
Neurotransmitter agents
Issue Date10-Nov-2017
CitationFrontiers in Neuroscience 11 (2017)
AbstractMolecular changes associated with neuronal aging lead to a decrease in cognitive capacity. Here we discuss these alterations at the level of brain regions, brain cells, and brain membrane and cytoskeletal proteins with an special focus in NMDA molecular changes through aging and its effect in cognitive decline and Alzheimer disease. Here, we propose that some neurodegenerative disorders, like Alzheimer's disease (AD), are characterized by an increase and acceleration of some of these changes.
Identifiersdoi: 10.3389/fnins.2017.00626
issn: 1662-453X
Appears in Collections:(CBM) Artículos
Files in This Item:
File Description SizeFormat 
ÁvilaJ_CognitiveDeclilneInNeuronal.pdf501,23 kBAdobe PDFThumbnail
Show full item record
Review this work

Related articles:

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.