English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/165074
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Effect of Fish Collagen Hydrolysates on Type I Collagen mRNA Levels of Human Dermal Fibroblast Culture

AuthorsSánchez, Ana Cristina ; Blanco Comesaña, M. ; Correa, Begoña ; Pérez Martín, Ricardo Isaac ; González Sotelo, Carmen
Issue Date26-Apr-2018
PublisherMultidisciplinary Digital Publishing Institute
CitationMarine Drugs 16 (5): 144 (2018)
AbstractFish discards and subproducts may represent an important source of raw material, not only for the food industry, but for other different kind of industries, such as the nutraceutical and cosmetic industries. Collagen, which is mainly obtained from animal skins, is an important structural protein in the animal kingdom having many different applications. It is well known that fish skins constitute a significant subproduct in the fishery industry, especially in the case of some species, where fish skins may represent up to 20% of the total body weight of fish. Peptides from collagen hydrolysates have been described to be useful for preventing skin aging and osteoarthritis, however, the mechanism for these biological activities is not well known. Fibroblasts are the main cell types involved in the collagen synthesis, and in the present work, human dermal fibroblasts have been exposed to the treatment of collagen peptides of two different molecular weight ranges. Results show that higher molecular weight collagen peptides produce higher synthesis of collagen type I mRNA and, therefore, it may suggest that prior molecular weight selection may be an important step to maximize the effect of collagen hydrolysates on collagen type I synthesis by dermal fibroblasts.
Publisher version (URL)http://dx.doi.org/10.3390/md16050144
DOIhttp://dx.doi.org/doi: 10.3390/md16050144
Identifiersdoi: 10.3390/md16050144
Appears in Collections:(IIM) Artículos
Files in This Item:
File Description SizeFormat 
marinedrugs-16-00144.pdf1,64 MBAdobe PDFThumbnail
Show full item record
Review this work

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.