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http://hdl.handle.net/10261/164505
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Bertocchini, Federica | - |
dc.contributor.author | Chuva de Sousa Lopes, Susana M. | - |
dc.date.accessioned | 2018-05-08T07:40:05Z | - |
dc.date.available | 2018-05-08T07:40:05Z | - |
dc.date.issued | 2016 | - |
dc.identifier | doi: 10.1002/bies.201600025 | - |
dc.identifier | e-issn: 1521-1878 | - |
dc.identifier | issn: 0265-9247 | - |
dc.identifier.citation | BioEssays 38(8): 791-800 (2016) | - |
dc.identifier.uri | http://hdl.handle.net/10261/164505 | - |
dc.description.abstract | In the field of germline development in amniote vertebrates, primordial germ cell (PGC) specification in birds and reptiles remains controversial. Avians are believed to adopt a predetermination or maternal specification mode of PGC formation, contrary to an inductive mode employed by mammals and, supposedly, reptiles. Here, we revisit and review some key aspects of PGC development that channelled the current subdivision, and challenge the position of birds and reptiles as well as the ‘binary’ evolutionary model of PGC development in vertebrates. We propose an alternative view on PGC specification where germ plasm plays a role in laying the foundation for the formation of PGC precursors (pPGC), but not necessarily of PGCs. Moreover, inductive mechanisms may be necessary for the transition from pPGCs to PGCs. Within this framework, the implementation of data from birds and reptiles could provide new insights on the evolution of PGC specification in amniotes. | - |
dc.description.sponsorship | This study was funded by grants from the Spanish Ministry of Science and Innovation (BFU2010-19656) and the Fundacion Areces to FB, and Interuniversity Attraction Poles-Phase VII [IUAP/PAI P7/14] to SMCdSL. | - |
dc.publisher | Wiley-VCH | - |
dc.relation.isversionof | Publisher's version | - |
dc.rights | openAccess | - |
dc.subject | Mammals | - |
dc.subject | Amniotes | - |
dc.subject | Chickens | - |
dc.subject | Epigenesis | - |
dc.subject | Evolution | - |
dc.subject | Preformation | - |
dc.subject | Primordial germ cells | - |
dc.title | Germline development in amniotes: A paradigm shift in primordial germ cell specification | - |
dc.type | artículo | - |
dc.identifier.doi | 10.1002/bies.201600025 | - |
dc.relation.publisherversion | https://doi.org/10.1002/bies.201600025 | - |
dc.date.updated | 2018-05-08T07:40:05Z | - |
dc.description.version | Peer Reviewed | - |
dc.language.rfc3066 | eng | - |
dc.rights.license | http://creativecommons.org/licenses/by/4.0/ | - |
dc.contributor.funder | Belgian Science Policy Office | - |
dc.contributor.funder | Ministerio de Ciencia e Innovación (España) | - |
dc.contributor.funder | Fundación Ramón Areces | - |
dc.relation.csic | Sí | - |
dc.identifier.funder | http://dx.doi.org/10.13039/100008054 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100004837 | es_ES |
dc.identifier.pmid | 27273724 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.fulltext | With Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.openairetype | artículo | - |
Aparece en las colecciones: | (IBBTEC) Artículos |
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Fichero | Descripción | Tamaño | Formato | |
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germlinespecif.pdf | 554,65 kB | Adobe PDF | Visualizar/Abrir |
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