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Three-dimensional OCT based Guinea pig eye model: Relating morphology and optics

AutorPérez Merino, Pablo ; Velasco Ocaña, Miriam ; Martínez-Enríquez, Eduardo ; Revuelta, Luis ; McFadden, Sally A.; Marcos, Susana
Fecha de publicación15-mar-2017
EditorOptical Society of America
CitaciónBiomedical Optics Express 8: 2173-2184 (2017)
ResumenCustom Spectral Optical Coherence Tomography (SOCT) provided with automatic quantification and distortion correction algorithms was used to measure the 3-D morphology in guinea pig eyes (n = 8, 30 days; n = 5, 40 days). Animals were measured awake in vivo under cyclopegia. Measurements showed low intraocular variability (<4% in corneal and anterior lens radii and <8% in the posterior lens radii, <1% interocular distances). The repeatability of the surface elevation was less than 2 µm. Surface astigmatism was the individual dominant term in all surfaces. Higher-order RMS surface elevation was largest in the posterior lens. Individual surface elevation Zernike terms correlated significantly across corneal and anterior lens surfaces. Higher-order-aberrations (except spherical aberration) were comparable with those predicted by OCT-based eye models.
Descripción12 pags., 6 figs., 3 tabs. -- OCIS codes: (110.4500) Optical coherence tomography, (110.6880) Three-dimensional image acquisition, (100.2960) Image analysis, (330.7327) Visual optics, ophthalmic instrumentation, (330.7324) Visual optics, comparative animal models, (330.5370) Physiological optics
URIhttp://hdl.handle.net/10261/164090
Identificadoresdoi: 10.1364/BOE.8.002173
issn: 2156-7085
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