English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/163851
Share/Impact:
Statistics
logo share SHARE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Integrating epigenetics into aquaculture research

AuthorsPiferrer, Francesc ; Anastasiadi, Dafni ; Díaz, Noelia ; Ribas, Laia
KeywordsDNA methylation
miRNAs
Epigenetic marks
Transgenerational effects
Animal farming
Histone modifications
Issue DateApr-2017
PublisherElsevier
CitationAquaculture 472(Suppl.1): 84-85 (2017)
AbstractEpigenetics is an exciting and fast developing area of biology that deals with the study of changes in gene expression and function that, nevertheless, do not involve alterations of the genotype. These changes can be heritable through cell mitoses and meiosis and thus through individual generations. Three major epigenetic mechanisms that can activate or suppress gene expression are recognized: DNA methylation, modification of chromatin structure through changes in histone proteins, and regulatory processes mediated by small RNAs. Epigenetic changes are being actively studied in some areas of biology such as developmental biology and for its implications in human health, notably in cancer. However, less attention has been paid in other fields, including evolutionary biology, ecology and, pertaining to our interest, animal production. Since epigenetic processes have been found to be responsible for the integration of both biotic and abiotic factors, epigenetics can help to understand how organisms respond a particular environment. In addition, epigenetic variation may explain the phenotypic variation in production-relevant traits observed in farmed populations. Thus, epigenetic variation can be considered in the light of selection programs to increase animal production. Particularly interesting is the link between conditions during early development, where many heritable epigenetic marks are established, and gene function later in life since proper management of these early conditions may contribute to better growth and health of farmed animals. Because of their external fertilization, aquatic animals in general and fish in particular are excellent research subjects where to study epigenetic changes. These various aspects of epigenetics will be discussed. Among others, an example will be provided on how modifications of a major environmental cue such as temperature is integrated through an epigenetic mechanism, ultimately determining phenotypic sex and growth in a production fish
DescriptionTwelfth International Symposium on Genetics in Aquaculture 2015 (ISGA XII), 21-27 June 2015, Santiago de Compostela, Spain.-- 2 pages
Publisher version (URL)https://doi.org/10.1016/j.aquaculture.2017.03.032
URIhttp://hdl.handle.net/10261/163851
Identifiersdoi: 10.1016/j.aquaculture.2017.03.032
issn: 0044-8486
Appears in Collections:(ICM) Artículos
Files in This Item:
There are no files associated with this item.
Show full item record
Review this work
 


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.