Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/163478
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Coordinated morphogenetic mechanisms shape the vertebrate eye |
Autor: | Martínez-Morales, Juan Ramón CSIC ORCID; Cavodeassi, Florencia CSIC ORCID; Bovolenta, Paola CSIC ORCID | Palabras clave: | Eye development Cell movement Morphogenesis Patterning Retina pigment epithelim Vertebrates Cell shape |
Fecha de publicación: | 2017 | Editor: | Frontiers Media | Citación: | Frontiers in Neuroscience 11: 721 (2017) | Resumen: | The molecular bases of vertebrate eye formation have been extensively investigated during the past 20 years. This has resulted in the definition of the backbone of the gene regulatory networks controlling the different steps of eye development and has further highlighted a substantial conservation of these networks among vertebrates. Yet, the precise morphogenetic events allowing the formation of the optic cup from a small group of cells within the anterior neural plate are still poorly understood. It is also unclear if the morphogenetic events leading to eyes of very similar shape are indeed comparable among all vertebrates or if there are any species-specific peculiarities. Improved imaging techniques have enabled to follow how the eye forms in living embryos of a few vertebrate models, whereas the development of organoid cultures has provided fascinating tools to recapitulate tissue morphogenesis of other less accessible species. Here, we will discuss what these advances have taught us about eye morphogenesis, underscoring possible similarities and differences among vertebrates. We will also discuss the contribution of cell shape changes to this process and how morphogenetic and patterning mechanisms integrate to assemble the final architecture of the eye. | Versión del editor: | https://doi.org/10.3389/fnins.2017.00721 | URI: | http://hdl.handle.net/10261/163478 | DOI: | 10.3389/fnins.2017.00721 | Identificadores: | doi: 10.3389/fnins.2017.00721 e-issn: 1662-453X issn: 1662-4548 |
Aparece en las colecciones: | (CABD) Artículos (CBM) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
cooreye.pdf | 1,16 MB | Unknown | Visualizar/Abrir |
CORE Recommender
PubMed Central
Citations
20
checked on 14-mar-2024
SCOPUSTM
Citations
26
checked on 15-mar-2024
WEB OF SCIENCETM
Citations
24
checked on 26-feb-2024
Page view(s)
259
checked on 18-mar-2024
Download(s)
201
checked on 18-mar-2024
Google ScholarTM
Check
Altmetric
Altmetric
Artículos relacionados:
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.