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Gene dosis and the timing of mitosis

AuthorsTallada, Víctor A. CSIC ORCID; Bähler, Jürg
KeywordsS. pombe
Cell size
G2-M transition
Genetic screen
Mitotic entry
Rate-limiting genes
Nucleotide metabolism
Nuclear transport
Issue Date2016
CitationCell Cycle 15(22): 3022-3023 (2016)
AbstractIn all organisms, cell size is crucial for biological function and is tightly controlled by genetic, environmental and physiological factors. Cell-size homeostasis is mediated by a finely balanced coordination between cell growth and division. At a critical point in the cell cycle, the G2-M transition, cells stop growth and enter mitosis; advancing or delaying this transition leads to smaller or larger cells, respectively
DescriptionCell Cycle News & Views
Publisher version (URL)
Identifiersdoi: 10.1080/15384101.2016.1252580
e-issn: 1551-4005
issn: 1538-4101
Appears in Collections:(CABD) Artículos

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