English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/162841
COMPARTIR / IMPACTO:
Estadísticas
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Título

Decreased adult neurogenesis in hibernating Syrian hamster

AutorLeón-Espinosa, G.; García, E.; Gómez-Pinedo, Ulises; Hernández, F.; DeFelipe, Javier ; Ávila, Jesús
Palabras claveneurogenesis
hibernation
Syrian hamster
Fecha de publicación2016
CitaciónNeuroscience 333: 181- 192 (2016)
ResumenGeneration of new neurons from adult neural stem cells occurs in the dentate gyrus (DG) of the hippocampus and the lateral walls of the lateral ventricles. In this article, we study the neurogenesis that takes place during the hibernation of the Syrian hamster (Mesocricetus auratus). Using a variety of standard neurogenesis markers and 5-bromo-2-deoxyuridine (BrdU) incorporation, we describe a preferential decrease in the proliferation of newborn neurons in the subventricular zone (SVZ) of the hibernating hamsters (torpor) rather than in the hippocampus. Furthermore, we demonstrate that the proliferative capacity is recovered after 3–4 days of torpor when arousal is triggered under natural conditions (i.e., not artificially provoked). In addition, we show that tau3R, a tau isoform with three microtubule-binding domains, is a suitable marker to study neurogenesis both in the SVZ and subgranular zone (SGZ) of the Syrian hamster brain.
URIhttp://hdl.handle.net/10261/162841
Identificadoresdoi: 10.1016/j.neuroscience.2016.07.016
issn: 1873-7544
Aparece en las colecciones: (IC) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
accesoRestringido.pdf15,38 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 

Artículos relacionados:


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.