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The dendritic spine story: An intriguing process of discovery

AutorDeFelipe, Javier
Palabras clavereticular theory
pyramidal cells
neuron doctrine
history of neuroscience
granule cells
Purkinje cells
Cajal
Golgi
Fecha de publicación2015
EditorFrontiers Media
CitaciónFrontiers in neuroanatomy 9 (2015)
Resumen© 2015 DeFelipe. Dendritic spines are key components of a variety of microcircuits and they represent the majority of postsynaptic targets of glutamatergic axon terminals in the brain. The present article will focus on the discovery of dendritic spines, which was possible thanks to the application of the Golgi technique to the study of the nervous system, and will also explore the early interpretation of these elements. This discovery represents an interesting chapter in the history of neuroscience as it shows us that progress in the study of the structure of the nervous system is based not only on the emergence of new techniques but also on our ability to exploit the methods already available and correctly interpret their microscopic images.
URIhttp://hdl.handle.net/10261/162144
Identificadoresdoi: 10.3389/fnana.2015.00014
issn: 1662-5129
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