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dc.contributor.authorZabalgogeazcoa, Iñigoes_ES
dc.contributor.authorÁlvarez Pascua, Amadores_ES
dc.contributor.authorHerrero Asensio, Noemíes_ES
dc.contributor.authorVázquez de Aldana, Beatriz R.es_ES
dc.date.accessioned2018-03-09T09:12:26Z-
dc.date.available2018-03-09T09:12:26Z-
dc.date.issued2018-
dc.identifier.citationMycotoxin Research 34(1): 49-57 (2018)es_ES
dc.identifier.issn0178-7888-
dc.identifier.urihttp://hdl.handle.net/10261/161895-
dc.description21 páginas, 3 tablas, 1 figura. -- This is a post-peer-review, pre-copyedit version of an article published in Mycotoxin Research. The final authenticated version is available online at: http://dx.doi.org/10.1007/s12550-017-0298-6es_ES
dc.description.abstractFumonisins were first discovered in Fusarium verticillioides, a fungus associated to disease and asymptomatic infections in maize. Afterwards, other fungal taxa have been found to produce fumonisins. The entomopathogenic ascomycete Tolypocladium cylindrosporum has been isolated from soil and also as an endophyte from leaves of grasses. The objectives of this work were to determine the in vitro production of fumonisin B (FB) mycotoxins and the immunosuppressive compound cyclosporine A (CyA) in several strains of T. cylindrosporum, and to examine the effect of fungal virus infection and temperature in FB production. FB1 was detected in 30% of the strains, ranging from 0.16 to 5.52 μg cm−2 in solid media, and FB2 was detected in 78% of the strains, ranging from 0.764 to 40.92 μg cm−2. CyA was not detected in any strain. The mean FB2 concentration of the endophytic strain Tc37W was three times greater (p < 0.05) than that of any other strain. Up to 34% more of FB2 was detected in strains infected by the virus TcV3 than in the corresponding virus-free versions. The effect of temperature on FB2 content was interactively significantly dependent on fungal strain and growth medium; in the YES medium, the FB2 of virus-infected strains Tc37-1V and Tc37W increased by 67 and 16%, respectively, at 26 °C as compared to 20 °C. The FB concentration in some fungal strains was similar to that in fungi associated to food and feed intoxications.es_ES
dc.description.sponsorshipThis research was funded by the Spanish Ministry of Economy and Competitiveness and cofounded by the European Regional Development Fund (project AGL2011-22783).es_ES
dc.language.isoenges_ES
dc.publisherSpringeres_ES
dc.relation.isversionofPostprintes_ES
dc.rightsopenAccessen_EN
dc.subjectCyclosporine Aes_ES
dc.subjectEndophytees_ES
dc.subjectGrasseses_ES
dc.subjectMycoviruses_ES
dc.subjectTemperature effectes_ES
dc.titleProduction of fumonisins by endophytic strains of Tolypocladium cylindrosporum and its relation to fungal virus infectiones_ES
dc.typeartículoes_ES
dc.identifier.doi10.1007/s12550-017-0298-6-
dc.description.peerreviewedPeer reviewedes_ES
dc.relation.publisherversionhttp://dx.doi.org/10.1007/s12550-017-0298-6es_ES
dc.identifier.e-issn1867-1632-
dc.embargo.terms2019-03-01es_ES
dc.contributor.funderEuropean Commissiones_ES
dc.contributor.funderMinisterio de Economía, Industria y Competitividad (España)es_ES
dc.relation.csices_ES
oprm.item.hasRevisionno ko 0 false*
dc.identifier.funderhttp://dx.doi.org/10.13039/501100000780es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100010198es_ES
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