Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/160383
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Preparation and characterization of maleoylagarose/PNIPAAm graft copolymers and formation of polyelectrolyte complexes with chitosan |
Autor: | Ortiz, J. A.; Matsuhiro, B.; Zapata, P. A.; Corrales, Teresa CSIC ORCID; Catalina, Fernando CSIC ORCID | Palabras clave: | Maleoylation NIPAAm Graft copolymerization Hydrogels Chitosan Agarose |
Fecha de publicación: | 2018 | Editor: | Elsevier | Citación: | Carbohydrate Polymers 182: 81-91 (2018) | Resumen: | A water soluble derivative in 98% yield with 23.1% incorporation of maleoyl groups was obtained by esterification of agarose with maleic anhydride. Graft copolymers were synthesized through vinyl groups of maleoylagarose with N-isopropylacrylamide using ceric ammonium nitrate or ammonium persulfate as initiator, by conventional method or microwave irradiation. High nitrogen content (4.6%) was obtained in the grafting process using ceric ammonium nitrate as initiator without microwave irradiation. Copolymers were characterized by FT-IR and NMR spectroscopies, TGA, DSC and morphological analysis by AFM and SEM microscopy, confirming the grafting of PNIPAAm onto polysaccharide backbone. Hydrogel films were obtained by ionic complexation between opposite charged groups of maleoylagarose-g-poly(N-isopropylacrylamide) and chitosan. The swelling of 1:1 w/v maleoylagarose-g-PNIPAAm:chitosan film was higher than 2:1 w/v film at 25 and 37 °C. 53% release in vitro of diclofenac sodium from 1:1 w/v maleoylagarose-g-PNIPAAm:chitosan was obtained at 37 °C and pH 6.0 with <0.5 diffusional constant values. | Versión del editor: | http://dx.doi.org/10.1016/j.carbpol.2017.11.012 | URI: | http://hdl.handle.net/10261/160383 | DOI: | 10.1016/j.carbpol.2017.11.012 | Identificadores: | doi: 10.1016/j.carbpol.2017.11.012 issn: 0144-8617 e-issn: 1879-1344 |
Aparece en las colecciones: | (ICTP) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
accesoRestringido.pdf | 15,38 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
20
checked on 01-abr-2024
WEB OF SCIENCETM
Citations
19
checked on 18-feb-2024
Page view(s)
285
checked on 19-abr-2024
Download(s)
124
checked on 19-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.