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Title

New Agents Active against African Swine Fever Virus

AuthorsSola, Ana; Rodríguez, Silvia; Gil-Fernández, Carmen; Alarcón, Balbino ; González, María Eugenia; Carrasco, Luis
Issue Date14-Nov-1985
PublisherAmerican Society for Microbiology
CitationAntimicrobial Agents and Chemotherapy
AbstractActinobolin, atropine, carrageenan, megalomycin C, suramin, and tetracenomycin C were tested for their activity against African swine fever virus replication. Both viral inhibitory potency and cytotoxicity were investigated. Megalomycin C, suramin, atropine, and carrageenan exhibited significant activity. Megalomycin C was the most active of the four agents with respect to the concentration of compound that blocked the formation of infectious virus by 50%. Suramin was the next most active agent in this respect, but because of its lower cytotoxicity, it had the most favorable therapeutic index
URIhttp://hdl.handle.net/10261/159313
ISSN0066-4804
Appears in Collections:(CBM) Artículos
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