English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/159276
Share/Impact:
Statistics
logo share SHARE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Title

Assessing the hyperthermic properties of magnetic heterostructures: the case of gold-iron oxide composites

AuthorsFantechi, Elvira; Castillo Hernández, Paula Margarita; Casula, Maria Francesca
Issue Date2016
PublisherRoyal Society (Great Britain)
CitationInterface Focus 6(6): 20160058 (2016)
AbstractGold-iron oxide composites were obtained by in situ reduction of an Au(III) precursor by an organic reductant (either potassium citrate or tiopronin) in a dispersion of preformed iron oxide ultrasmall magnetic (USM) nanoparticles. X-ray diffraction,transmission electron microscopy,chemical analysis and mid-infrared spectroscopy show the successful deposition of gold domains on the preformed magnetic nanoparticles,and the occurrence of either citrate or tiopronin as surface coating. The potential of the USM@Au nanoheterostructures as heat mediators for therapy through magnetic fluid hyperthermia was determined by calorimetric measurements under sample irradiation by an alternating magnetic field with intensity and frequency within the safe values for biomedical use. The USM@Au composites showed to be active heat mediators for magnetic fluid hyperthermia,leading to a rapid increase in temperature under exposure to an alternating magnetic field even under the very mild experimental conditions adopted,and their potential was assessed by determining their specific absorption rate (SAR) and compared with the pure iron oxide nanoparticles. Calorimetric investigation of the synthesized nanostructures enabled us to point out the effect of different experimental conditions on the SAR value,which is to date the parameter used for the assessment of the hyperthermic efficiency.
URIhttp://hdl.handle.net/10261/159276
Identifiersdoi: 10.1098/rsfs.2016.0058
e-issn: 2042-8901
Appears in Collections:(CABIMER) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.