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Application of EARL (ResEARch 4 Life®) approved and rejected protocols for [18F]FDG-PET/CT clinical and research studies

AuthorsBalcerzyk, Marcin ; Fernández-López, Rosa; Parrado-Gallego, Ángel; Chavero Royan, José; Hevilla, Juan; Jiménez Ortega, Elisa; Leal, Antonio
Issue Date2016
CitationImaging 2016
AbstractIn adjusting the available acquisition and reconstruction protocols to EARL (ResEARch 4 Life ®, http://earl.eanm.org) [18F]FDG-PET/CT accreditation we also tried to develop a protocol which maximises Recovery Coefficient (RC) for Image Quality NEMA 2007 phantom. We used Siemens Biograph mCT PET/CT clinical scanner with Syngo V51C acquisition software. The scanner and software apart from typical corrections allows Time of Flight correction, iterative OSEM reconstruction and application of Point Spread Function. The protocol fulfilling EARL requirements was developed and also the research protocol optimizing RC for mean Standard Uptake Value (SUV) and maximum SUV being as close to 1 as possible for both SUV types simultaneously and for NEMA 2007 phantom spheres of 17 mm diameter and larger. For all developed protocols we assessed the differences in mean and maximum SUV for small diameter and low metabolic rate tumours in several clinical cases. Additionally, we evaluated the differences in other tumour parameters derived from VOI and ROI delineation like dimensions and volume. An estimation of predictive value by using EARL accreditation protocol facing the research protocol is being carried out.
DescriptionResumen del trabajo presentado a la international conference on imaging techniques in subatomic physics, astrophysics, medicine, biology and industry; celebrada en Estocolmo (Suecia) del 13 al 16 de junio de 2016.
Appears in Collections:(CNA) Comunicaciones congresos
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