English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/158215
logo share SHARE   Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:


Mass spectrometry-based lipidomic approaches to identify lipid markers of inflammation

AuthorsBalsinde, Jesús
Issue Date2016
CitationPrograma de Pós-Graduaçâo em Imunologia Básica e Aplicada (2016)
AbstractMass spectrometry (MS) in combination with liquid chromatography (LC), or LC/MS, is the preferred technique for lipidomic analyses. One of the most used applications of lipidomics is the search for molecular markers that can be used to signal specific activation states and that, ultimately, can be used in the early diagnosis of diseases. Our recent studies with monocytes/macrophages stimulated by inflammatory stimuli have revealed changes that result in the accumulation of unusual lipids. These changes are sometimes stimulus-specific and thus, could be regarded as specific markers of activation. Two examples are discussed below that resulted from the lipidomic analysis of arachidonate-containing phospholipids, and the analysis of the fatty acid composition of neutral lipids accumulating in cytoplasmic lipid droplets.
DescriptionTranscription of the talk presented on Thursday October 27, 2016 at the Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (Brazil).
Appears in Collections:(IBGM) Comunicaciones congresos
Files in This Item:
File Description SizeFormat 
Masspectrometrybased.pdf126,1 kBAdobe PDFThumbnail
Show full item record
Review this work

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.