Synthesis of functionalized cyclopropanes from unsaturated fatty esters

Abstract

[Conclusions]: -It has been possible to carry out the cyclopropanation reaction between different fatty esters and ethyl diazoacetate (EDA) in only one step with quantitative yields, using 1% of catalyst (Cu(OTf)2) and mild conditions. -The cyclopropanation with methyl diazomalonate (MDM) needed harsher reaction conditions because of the lower reactivity of this reagent. Even so, we were able to obtain yields from moderate to excellent. -The products obtained in the cyclopropanation reaction have been easily transformed into diacids, triacids, diols and triols. These compounds have the potential to be used as monomers or comonomers in polymerization reactions for the obtaining of new materials.