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Virulence-specific cell cycle and morphogenesis connections in pathogenic fungi

AuthorsPérez-Martín, José ; Bardetti, Paola; Castanheira, Sónia; Torre, Antonio de la; Tenorio-Gómez, María
KeywordsMagnaporthe oryzae
Candida albicans
Ustilago maydis
Fungal virulence
Cell cycle
Issue Date2016
CitationSeminars in Cell and Developmental Biology 57: 93-99 (2016)
AbstractTo initiate pathogenic development, pathogenic fungi respond to a set of inductive cues. Some of them are of an extracellular nature (environmental signals), while others are intracellular (developmental signals). These signals must be integrated into a single response whose major outcome is changes in the morphogenesis of the fungus. The regulation of the cell cycle is pivotal during these cellular differentiation steps; therefore, cell cycle regulation would likely provide control points for infectious development by fungal pathogens. Here, we provide clues to understanding how the control of the cell cycle is integrated with the morphogenesis program in pathogenic fungi, and we review current examples that support these connections.
Publisher version (URL)https://doi.org/10.1016/j.semcdb.2016.03.017
Identifiersdoi: 10.1016/j.semcdb.2016.03.017
e-issn: 1096-3634
issn: 1084-9521
Appears in Collections:(IBFG) Artículos
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