Regioselective functionalisation and protection of spirolactams

Abstract

The invention provides highly functionalised spiro-fused lactams of formula (1) having a cyclohexane moiety with the desired number of protected or unprotected functional groups or carbonated structures, which are introduced with high stereo and regioselectivity, as well as processes for their obtention. These compounds are useful for the synthesis of a broad range ofbioactive molecules, such as condoritols and aminoinositols and their analogues.